1H-[1,2,4]Triazole-3-sulfonic acid amide

1H-[1,2,4]Triazole-3-sulfonic acid amide - Names and Identifiers

Name	1H-1,2,4-triazole-3-sulfonamide
Synonyms	FLORASULAM METABOLITE TSA Florasulam Metabolite TSA 1H-1,2,4-triazole-3-sulfo... 1H-1,2,4-Triazole-5-sulfonamide 1H-1,2,4-triazole-3-sulfonamide 1H-1,2,4-triazole-3-sulfonaMide 1H-1,2,4-Triazole-3-sulfonamide(9CI) 1H-[1,2,4]Triazole-3-sulfonic acid amide
CAS	89517-96-4

1H-[1,2,4]Triazole-3-sulfonic acid amide - Physico-chemical Properties

Molecular Formula	C2H4N4O2S
Molar Mass	148.14
Density	1.781±0.06 g/cm3(Predicted)
Melting Point	224.5-225.5 °C(Solv: water (7732-18-5))
Boling Point	487.3±28.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White
pKa	7.00±0.20(Predicted)
Storage Condition	2-8°C

1H-[1,2,4]Triazole-3-sulfonic acid amide - Introduction

1H-1,2,4-triazole-3-sulfonamide is a chemical substance with the following properties:
-Appearance: Colorless crystal or crystalline powder.
-Solubility: Soluble in water and some organic solvents, such as alcohols and ethers.
-Melting point: approximately between 120-130 degrees Celsius.

The main uses of 1H-1,2,4-triazole-3-sulfonamide are:
-Pharmaceutical field: It can be used as raw materials and intermediates for antibacterial drugs, pesticides and anti-tumor drugs.
-Pesticide field: It can be used for the preparation of pesticides and fungicides in agriculture.
-Dye field: It can be used as a dye intermediate.

Preparation method of 1H-1,2,4-triazole-3-sulfonamide:
A common preparation method is to react 1,2,4-triazole with sulfonyl chloride to generate 1H-1,2,4-triazole-3-sulfonyl chloride, subsequent reaction with ammonia or an amine compound gives the target product 1H-1,2,4-triazole-3-sulfonamide.

About safety information:
-As a chemical substance, the compound should be used in a suitable laboratory or industrial environment and follow relevant safe operating procedures.
-Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, flush immediately with plenty of water and seek medical help.
-When storing and handling the compound, follow proper safety and precautions to ensure leakage and accidents are avoided.
-Personal protective equipment such as lab gloves, goggles and protective masks should be used when using the compound to ensure safe use.

Last Update：2024-04-09 20:00:08